:: (The study describes 11 coronavirus sequences from five Brazilian states. Each had revealing changes in the virus receptor, making it one of the known variants …): Health


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The study describes 11 coronavirus sequences from five Brazilian states. Each had telltale changes in the virus receptor, making it one of the known variants. But each also had additional changes in another important region of the virus known as the N-terminal domain (NTD). The changes were deletions of important antibody binding sites …

March 24, 2021 – The uncontrolled spread of the most contagious coronavirus variants in Brazil appears to have created even more dangerous versions of the virus that causes COVID-19.

https://virological.org/t/the-ongoing-evolution-of-variants-of-concern-and-interest-of-sars-cov-2-in-brazil-revealed-by-convergent-indels-in- the-n-terminal-amino-domain-of-the-spike-protein / 659

A team of researchers from Fiocruz, a large public health research laboratory run by the Brazilian Ministry of Health, documented the changes. Their results were recently published in a prepublication on Virological.org, ahead of peer review. The study describes 11 coronavirus sequences from five Brazilian states. Each had telltale changes in the virus receptor, making it one of the known variants. But each also had additional changes in another important region of the virus known as the N-terminal domain (NTD). The changes were deletions of important antibody binding sites. Many of these were key deletions of a mutation that appeared independently in other circulating variants and that has been observed in viral mutations in recovering cancer patients, suggesting that it confers a significant advantage on the virus. …



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